Modular Elastic Patches: Mechanical and Biological Effects

Elastic proteins: biological roles and mechanical properties.

The term 'elastic protein' applies to many structural proteins with diverse functions and mechanical properties so there is room for confusion about its meaning. Elastic implies the property of elasticity, or the ability to deform reversibly without loss of energy; so elastic proteins should have high resilience. Another meaning for elastic is 'stretchy', or the ability to be deformed to large ...

Modular assembly of thick multifunctional cardiac patches.

In cardiac tissue engineering cells are seeded within porous biomaterial scaffolds to create functional cardiac patches. Here, we report on a bottom-up approach to assemble a modular tissue consisting of multiple layers with distinct structures and functions. Albumin electrospun fiber scaffolds were laser-patterned to create microgrooves for engineering aligned cardiac tissues exhibiting anisot...

Modeling of biological doses and mechanical effects on bone transduction.

Shear stress, hormones like parathyroid and mineral elements like calcium mediate the amplitude of stimulus signal, which affects the rate of bone remodeling. The current study investigates the theoretical effects of different metabolic doses in stimulus signal level on bone. The model was built considering the osteocyte as the sensing center mediated by coupled mechanical shear stress and some...

Mechanical and Biological Properties of Bio-Inspired Nano-Fibrous Elastic Materials from Collagen

Mechanical ventilation and elastic fiber assembly.

ELASTIN IS A CONSTITUENT of connective tissue that is present in virtually all vertebrate tissues and has an especially vital role in organs that undergo repeated cycles of extension and recoil such as the arteries, lungs, and skin. Elastic fibers consist of two morphologically distinct components, the microfibrils and polymerized tropoelastin. The current view is that elastin is secreted from ...